Aptima Combo 2 testing detected additional cases of Neisseria gonorrhoeae infection in men and women in community settings.
نویسندگان
چکیده
Aptima Combo 2 (AC2) Neisseria gonorrhoeae testing of 81,405 patients who were tested by culture and 14,666 who were AC2 tested for Chlamydia trachomatis detected 142 extra infections and confirmed 106 culture-positive samples (the positivity rate increased from 0.13 in testing by culture to 0.26 in testing by AC2). Retrievable AC2 positive samples were confirmed (98.5%) by an alternate AGC test.
منابع مشابه
Comparison of flocked and aptima swabs and two specimen transport media in the aptima combo 2 assay.
Self-collected vaginal Aptima swabs and flocked swabs in Aptima specimen transport medium and ESwabs in ESwab medium detected all 37 Chlamydia trachomatis-infected patients from 287 women tested by the Aptima Combo assay. Prevalence rates of C. trachomatis, Neisseria gonorrhoeae, and dual infection were 12.8%, 3.1%, and 2.4%, respectively.
متن کاملComparison of Flocked and Aptima Swabs and Two Specimen Transport Media in 1 the Aptima Combo 2 Assay 2 3 Running Title : AC 2 Testing of Swabs and Transport Media 4 5
42 Self-collected vaginal Aptima swabs and flocked swabs in Aptima specimen transport 43 media and ESwabs in ESwab media detected all 37 C. trachomatis infected patients 44 from 287 women tested by the Aptima Combo assay (n=287). Prevalence rates of C. 45 trachomatis, N. gonorrhoeae, and dual infection were 12.8%, 3.1% and 2.4%, 46
متن کاملPositive predictive value of Gen-Probe APTIMA Combo 2 testing for Neisseria gonorrhoeae in a population of women with low prevalence of N. gonorrhoeae infection.
We collected specimens from women who tested positive for Neisseria gonorrhoeae using the Gen-Probe APTIMA Combo 2 (AC2), and we performed confirmatory tests using a nucleic acid amplification test (NAAT) that targets alternate gonococcal nucleic acid sequences. Among 59,664 specimens, 280 (0.47%) had positive results using AC2; 265 of these specimens were tested using the confirmatory NAAT, of...
متن کاملUtility of specimens positive for Neisseria gonorrhoeae by the Aptima Combo 2 assay for assessment of strain diversity and antibiotic resistance.
In our jurisdiction, the Aptima Combo 2 assay (Gen-Probe, Inc.) is used to detect Neisseria gonorrhoeae from specimens collected at clinics for sexually transmitted infections (STI) and from select community patients. In addition, swabs are also collected for N. gonorrhoeae culture, susceptibility testing, and sequence typing (ST). Since only a small proportion of samples from provincial cases ...
متن کاملComparative performance of culture using swabs transported in Amies medium and the Aptima Combo 2 nucleic acid amplification test in detection of Neisseria gonorrhoeae from genital and extra-genital sites: a retrospective study.
BACKGROUND Nucleic acid amplification tests are being increasingly used for the routine diagnosis of Neisseria gonorrhoeae (GC), although culture remains essential for monitoring antimicrobial resistance. The authors investigated how symptoms and infection site influenced test sensitivity. METHODS This was a retrospective study at two centres of patients diagnosed as having GC by Aptima Combo...
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 49 5 شماره
صفحات -
تاریخ انتشار 2011